In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. There are different types of anemia, but IDA is the most common type. These side effects may include constipation and diarrhea. The oral form of the drug, called sucroferric oxyhydroxide and used . Also tell them about any vitamins, herbs, and supplements you use. intense abdominal pain. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Its because everyones body is different. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. You will be watched closely by your doctor for 30 minutes after each dose. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. There isnt a known interaction between Injectafer and alcohol. Pain, swelling, or redness at the injection site may occur. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. For more information about Injectafers approved uses, see the section Injectafer uses below. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Before taking Injectafer, talk with your doctor about your health history. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Sharing this information can help you avoid potential interactions. dizziness. Examples of thisinclude: Not allside effectslast forever. Taking a higher dose than needed can often lead to adverse effects. There are currently no generic forms of either drug. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Properly discard this product when it is expired or no longer needed. Venofer injection contains iron sucrose, a form of the mineral iron. Dating an Addict in Recovery: What to Expect Injectafer isnt available in a generic form. Do not exceed 1,500 mg of iron per dosing course. What Is the Cost of Whole Genome Sequencing (WGS)? After 5 weeks of treatment: This study didnt determine if either drug was better than the other. You should not receive Venofer if you have known allergies to iron sucrose. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Tell your doctor if you are pregnant or plan to become pregnant. Feeling awful 10 days after Iron Infusion. Is it normal? Any long-term side effects/dangers from iron infusions? Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. With IV infusion, the drug is given as a slow drip into your vein over a period of time. The study also didnt show if one treatment was worse than the other. However, be sure to take the dosage your doctor prescribes for you. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. wAd**CgI%"nn{Oa[q{r5 If you have questions about side effects, call your doctor. FG Trade/E+ sia Getty Images . Anyone had an adverse reaction to Venofer (iron sucrose) and how long Version: 7.01. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Renal elimination is negligible. Learn more about the types of tests and treatment. Consult the product instructions and your pharmacist for storage details. muscle pain. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. pain or burning at the injection site. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. VenAccess is a trademark of Vifor (International) Inc. Switzerland. No, you most likely wont take Injectafer long term. They can tell you about other medications that may work well for you. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Venofer infusions- how long does it take to notice improvement?? - Reddit These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). I used to get a different type but my . You may report side effects to the FDA at 1-800-332-1088. Other drugs are available that can treat iron deficiency anemia (IDA). Be ready to tell or show what was taken, how much, and when it happened. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. This medication is given by injection into a vein as directed by your doctor. Venofer pregnancy and breastfeeding warnings. If your symptoms or health problems do not get better or if they become worse, call your doctor. Nose or throat irritation. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. pain in the arms or legs. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Review our medical disclaimer. Infusions should be administered over at least 15 minutes. Tell all of your health care providers that you take Venofer. Joint pain. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. They can recommend appropriate treatment options. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. 2 0 obj You may also report side effects at https://www.fda.gov/medwatch. Someside effectsare temporary or last as long as the person continues takingprescription medicine. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Innovators Monograph Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. The following lists contain some of the key side effects that may occur while taking Injectafer. Venofer (iron sucrose): Basics, Side Effects & Reviews - GoodRx Storage Condition Store in a cool and dry place protected from light. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. Evenbirth controlcan lead to severeside effectslike bloodclots. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Venofer® (iron sucrose injection, USP) is available by prescription only. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. This is not a complete list of side effects and others may occur. How Long Do Immunotherapy Side Effects Last? | Cancer Today Check with your pharmacist. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. And these two doses need to be separated by at least 7 days. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Last updated August 20, 2020. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Iron infusion: Uses, benefits, and what to expect - Medical News Today 5 0 obj This information should not be used to decide whether or not to take Venofer or any other medicine. Its caused by your body not having enough iron, which is needed to make hemoglobin. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. The information provided is not intended to replace your healthcare provider's medical advice. endobj Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. This includes your doctors, nurses, pharmacists, and dentists. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. Depending on your anemia symptoms, your weight changes may be different than those described here. Following an LSD trip, users may experience a sort of 'comedown.'. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. One study of just under 5000 HRT users found that 43% were affected. (And Injectafer is used to treat IDA.) This is not a complete list of side effects and others may occur. You may report side effects to Health Canada at 1-866-234-2345. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. And this person had gotten their first dose of the drug without having an allergic reaction. Diarrhea. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Some products that may interact with this drug include: vitamin products, other iron-containing products. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. And this could lead to weight gain, if they increase their food intake. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. reese0809 1 yr. ago. All of the people took iron by mouth for 2 weeks. The infusion will take between 15-30 minutes if it is given in. Consult your pharmacist or local waste disposal company. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Call your doctor for medical advice about side effects. After the infusion, you can drive yourself home and return to your usual activities. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Its responsible for carrying oxygen throughout your body. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Wellbutrin: Side effects and how to manage them - Medical News Today This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This is not a complete list of possible side effects. Some drugs may have another patient information leaflet. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Intravenous Iron Infusion - Cleveland Clinic Venofer (iron sucrose) injection, USP | Patient Site Side effects of HRT | Stella In the study, peoples hemoglobin level was measured to check for improvement in their anemia. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Do not start, stop, or change the dosage of any medicines without your doctor's approval. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Venofer is used to treat iron deficiency anemia in people with kidney disease. As with most drugs, some people can have an allergic reaction after taking Injectafer. Venofer | Uses, Dosage, Side Effects, FAQ - MedicinesFAQ Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Iron Infusion: Benefits, Side Effects, and What to Expect - Healthline Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness.